Secuenciación del tratamiento en CPRC - page 32

ENZALUTAMIDA ABI/DOC o DOC/ABI
OS PFS
Response
Rate
PSA 50 No. pts Reff Author
8.3 mo 3.1 mo 11.8% 18% 137 Eur Urology 2014 Brasso
NR 2.8 mo 4.3% 12.8% 39 Eur J cancer 2014 Bianchini
7.1 4.0 mo 2.9% 28.6% 35 Eur Urology 2014 Schrader
7.5 mo 3.1 mo 2.8% 10% 35 Adv Ther 2014 Schmid
31.6 w 12 w NR 21% 61 Cancer 2014 Badrising
4.8 NA NR 25% 24 Scand J Urol 2014 Thomsen
8.5 mo 2.8 mo NR 39.1% 23 Eur J cancer 2014 Thomson
NR NR NR 26% 122 ASCO GU 2014 Heather H. Cheng
NR 15.07 W NR NA 75 ASCO GU 2014 Stevenson
NR 4.9 mo NR 27% 26 ASCO GU 2014 F.E Vera-Badillo
8.6 mo 6.6 mo NR 25.5% 68 Eur Urology 2015 Arun A. Azad
18.4 mo 8.3 29% 54% 1199
New Engl J of
Medicine 2012
Howard I. Scher
AFFIRM