CD8+ T cells in vivo transferred into tumor bearing mice are
recruited into the tumor but upregulate Foxp3
Naive
Pre-ACT
Tumor
Lymph nodes
0
2
4
6
8
10
5 days after ACT
p<0.05
p<0.005
%FOXP3+/CD45.1
B16OVA
OT-I T-cells
CD45.1
0
10 20 30
0
500
1000
1500
2000
OT-I Foxp3
wt
OT-I Foxp3
sf
Days after T cell transfer
Tumor volume (mm
3
)
Lozano et al, in preparation
