Locoregional treatment versus no treatment of the
primary tumour in metastatic breast cancer: an open-
label randomised controlled trial.
Conclusion:
There is no evidence to suggest that locoregional treatment of the primary
tumour affects overall survival in patients with metastatic breast cancer at
initial presentation who have responded to front-line chemotherapy, and this
procedure should not be part of routine practice.
2015 Oct;16(13):1380-8.
350 patients: 173 to locoregional treatment and 177 to no locoregional treatment
