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Guía OncoSur de sarcomas de partes blandas
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Low-grade fibromyxoid sarcoma
t(7;16)(q33;p11)
FUS-CREB3L2 fusion
Malignant peripheral nerve sheath
tumor
Complex
Myxofibrosarcoma (myxoid MFH)
Ring form of chromosome 12
Rhabdoid tumor
Deletion of 22q
INI1 inactivation
Rhabdomyosarcoma
Alveolar
t(2;13)(q35;q14)
t(1;13)(p36;q14),
double
minutes
t(2 ;2)(q35 ;p23)
PAX3-FOXO1A fusion
PAX7-FOXO1A fusion
PAX3-NCOA1 fusion
PAX3-AFX fusion
Embryonal
Trisomies 2q, 8 and 20
Loss of heterozygosity at
11p15
Solitary fibrous tumor
Inversion chromosome 12 NAB2-STAT6
Synovial sarcoma
Monophasic
t(X;18)(p11;q11)
SS18-SSX1, SS18-SSX2 or
SS18-SSX4 fusion
Biphasic
t(X;18)(p11;q11)
Predominantly SS18-SSX1
fusion
– Anexo 1 –
Characteristic cytogenetic and molecular events of soft tissue Tumors
(continuación)
PNET: primitive neuroectodermal tumor.